Busia is at the border of Kenya, adjacent to the similarly named town of Busia, Kenya. Busia, Uganda is approximately 195 Kilometres (121 miles), by road, east of Kampala, the capital and largest city of Uganda. This is approximately 50 Kilometres (31 miles), by road, south of the town of Tororo, the nearest large town in Uganda.

Busia stands at 0°28’01.0″N, 34°05’24.0″E (Latitude:0.4669; Longitude:34.0900). Busia, Uganda sits at an average elevation of 1,198 Metres (3,930 ft) above sea level.

The total area coverage for Busia Municipal Council is 7 km2. It has a population of 54,798 (National Population Census figures of 2014)